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Technical Data Sheet

Eastman™ Cellulose Acetate Butyrate (CAB-171-15NF)
Application/Uses
  • Osmotic drug delivery
  • Pharmaceutical excipient
  • Tableting, especially for sustained release
  • Taste-masking
Product Description
When cellulose is esterified with both acetyl and butyryl radicals to form the mixed ester, cellulose acetate butyrate, many of the desirable properties of both esters are obtained. Eastman™ Cellulose Acetate Butyrate CAB 171-15 National Formulary has the lowest butyryl content in the series of Eastman™ Cellulose Acetate Butyrates. It can be used as coating material as the semi-permeable membrane for osmotic drug delivery. It is also used for taste-masking and sustained release tableting. Eastman™ Cellulose Acetate Butyrate CAB-171-15 NF is made under cGMP and meets the requirements of the National Formulary (NF). Eastman™ Cellulose Acetate Butyrate CAB-171-15 NF is available in powder form.

Typical Properties
Property Test
Method
Typical Value, Units
Form        Solid (powder) 
Color        White 
Composition  
  Acetyl
  28-31%
  Hydroxyl
  0.8-1.4%
  Butyryl
  16.5-19%
  Moisture
  5.0 wt % max.
Solubility in Water        Negligible 
Viscosity      ASTM A  14-24 s

Comments
Properties reported here are typical of average lots. Eastman makes no representation that the material in any particular shipment will conform exactly to the values given.

Eastman and its marketing affiliates shall not be responsible for the use of this information, or of any product, method, or apparatus mentioned, and you must make your own determination of its suitability and completeness for your own use, for the protection of the environment, and for the health and safety of your employees and purchasers of your products. No warranty is made of the merchantability of fitness of any product, and nothing herein waives any of the Seller's conditions of sale.

08-Jul-2010 11:49:09 AM